| | | | | Fudan
University, Shanghai B.S. 1985 Genetics
Fudan University, Shanghai M.S. 1987
Genetics
University of Texas – Health Science Center at Houston, TX Ph.D.
1994 Genetics
Stanford University, CA Postdoc 1996 Genetics |
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| | Cheung
Kong Lecture Scholar, Hong Kong (2000)
Dean’s Excellence Award, University
of Texas – Houston (2000)
Excellence in Scholarship Award, School of Public
Health, University of Texas – Houston (2000)
White Magnolia Award for Promoting
Academic Exchange, Shanghai Municipal Government (1998, 1999, 2000)
Excellence
in Research Award, School of Public Health, University of Texas-Houston (1998,1999,2000)
Peer Recognition for Outstanding Scholarship Award, School of Public Health, University
of Texas – Houston (1999,2001)
Outstanding Young Researcher Award, Ministry
of Education, China (1998).
Outstanding Young Scientist Award, Li Foundation,
San Francisco, USA (1997). | | | |
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| | 2001–Present
Professor, Ctr. for Genome Information, Dept. of Environmental Health, Univ. of
Cincinnati, Cincinnati, OH
1999–2001 Associate Professor, Human Genetics
Center, School of Public Health, Univ. of Texas, Houston, TX
1997-Present
Adjunct Professor, Institute of Genetics, Fudan University, Shanghai
1997-1999
Assistant Professor, Human Genetics Center, School of Public Health, Univ. of
Texas, Houston, TX | | | |
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Books:
Jin L, Selestad M, Xiao C. 2001. Genetic, Linguistic and Archaeological Perspectives on Human
Diversity in Southeast Asia. World Scientific Press, Singapore, New York, London.
Journals:
Nei M, Jin L: Variances of the average numbers of nucleotide substitutions within
and between populations. Mol Biol Evol 1989; 6:290-300.
Jin L, Nei M: Limitations of the evolutionary parsimony method of phylogenetic analysis. Mol
Biol Evol 1990; 7:82-102.
Jin L, Nei M: Relative efficiencies of the
maximum parsimony and distance-matrix methods of phylogeny construction for restriction
data. Mol Biol Evol 1991;8:356-365.
Edwards A, Hammond HA, Jin L, Caskey
CT, Chakraborty R: Population genetics of trimeric and tetrameric tandem repeats
in four human ethnic groups. Genomics 1992;12:241-253.
Chakraborty R,
Jin L: Heterozygote deficiency, population substructure and their implications
in DNA fingerprinting. Hum Genet 1992 88:267-272.
Shriver MD, Jin L,
Chakraborty R, Boerwinkle E: Computer simulations of the stepwise mutation model
and VNTR allele frequency distributions. Genetics 1993;134:983-993.
Chakraborty R, Jin L: Determination of relatedness between individuals by DNA
fingerprinting. Hum Biol 1993;65:875-895.
Jin L, Chakraborty R: A bias-corrected
estimate of heterozygosity for single-probe multilocus DNA fingerprints. Mol Biol
Evol 1993;10:1112-1114.
Jin L, Chakraborty R: Estimation of genetic
distance and coefficient of gene diversity from single-probe multilocus DNA fingerprinting
data. Mol Biol Evol 1994;11:120-127.
Jin L, Chakraborty R: Population
dynamics of DNA fingerprinting patterns within and between populations. Genet
Res 1994;63:1-9.
Hammond HA, Jin L, Zhong Y, Caskey CT, Chakraborty R:
Evaluation of 13 STR loci for personal identification. Am J Hum Genet 1994;55:175-189.
Morin PA, Moore JJ, Chakraborty R, Jin L, Goodall J, Woodruff DS: Kin
selection, social structure, gene flow, and the evolution of chimpanzees. Science
1994;265:1193-1201.
Jin L, Zhong Y, Chakraborty R: The exact numbers
of possible microsatellite motifs. Am J Hum Genet 1994;55:582-583.
Deka
R, Jin L, Shriver MD, Yu LM, DeCroo S, Hundrieser J, Bunker CH, Ferrell RE, Chakraborty
R: Population genetics of dinucleotide (dC-dA)n(dG-dT)n polymorphisms in world
populations. Am J Hum Genet 1995;56:461-474.
Jin L, Chakraborty R: Population
structure, stepwise mutations, and heterozygote deficiency and their implications
in DNA forensics. Heredity 1995;74:274-285.
Shriver, M.D., L. Jin, R. Chakraborty, R. Deka, R.E. Ferrell, E. Boerwinkle: A novel measure of genetic distance for highly polymorphic tandem repeat loci. Mol Biol Evol 1995;12:914-920.
Underhill PA, Jin L, R Zemans, P Oefner, Cavalli-Sforza LL: A pre-Columbian
Y chromosome-specific transition and its implications for human evolutionary history.
Proc Natl Acad Sci USA 1995;93:196-200.
Deka R, Jin L, Shriver MD, Yu LM, Saha N, Barrantes R, Chakraborty R, Ferrell RE: Dispersion of human Y chromosome haplotypes based on five microsatellites in global populations. Genome Res 1996;6:1177-1184.
Jin L, Macaubas C, Hallmayer J, Kimura A, Mignot E: Mutation rate varies
among alleles at a microsatellite locus: Phylogenetic evidence. Proc Natl Acad
Sci USA 1996;93:15285-15288.
Underhill PA, Jin L, Lin A, Mehdi SQ, Jenkins
T, Vollrath D, Davis RW, Cavalli-Sforza LL, Oefner PJ: Detection of numerous Y
chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography.
Genome Res 1997;7:996-1005.
Chu JY, Huang W, Kuang SQ, Wang JM, Xu JJ,
Chu ZT, Yang ZQ, Lin KQ, Li P, Wu M, Geng ZC, Tan CC, Du RF, Jin L: Genetic Relationship
of Populations in China. Proc Natl Acad Sci USA 1998;95:11763-11768.
Su B, Chakraborty R, Xiao J, Lu D. Jin L: An HIV-resistant allele is exceptionally
frequent in New Guinean highlanders. J Am Med Asso (JAMA) 1998;280:1830.
Jin L, Underhill PA, Doctor V, Davis RW, Shen P, Cavalli-Sforza LL, Oefner
PJ: Distribution of haplotypes from a chromosome 21 region distinguishes multiple
prehistoric human migrations. Proc Natl Acad Sci USA 1999; 96:3796-3800.
Xiong M, Jin L: Comparison of the power and accuracy of biallelic and microsatellite
markers in population-based gene-mapping methods. Am J Hum Genet 1999;64:629-40.
Hacia JG, Fan J-B, Ryder O, Jin L, Edgemon K, Ghandour G, Mayer RA, Sun B,
Hsie L, Robbins CM, Brody LC, Wang D, Lander ES, Lipshutz R, Fodor SPA, Collins
FS: Determination of ancestral alleles for human single-nucleotide polymorphisms
using high-density oligonulceotide arrays. Nature Genet 1999;22:164-167.
Su B, Jin L, Xiao J, Hu F, Zhang W, Lu D, Luo J, Chu J, Du R, Geng Z, Qiu X, Xue
J, Tan CC, O’Brien SJ, Chakraborty R: Distribution of Two HIV-1 Resistant Polymorphisms
(SDF1-3’A and CCR2-64I) in East Asia and World Populations and Its Implication
in AIDS Epidemiology. Am J Hum Genet 1999;65:1047-1053.
Su B, Xiao J,
Underhill P, Deka R, Zhang W, Akey J, Huang W, Shen D, Lu D, Luo J, Chu J, Tan
J, Shen P, Davis R, Cavalli-Sforza LL, Chakraborty R, Xiong M, Du R, Oefner P,
Chen Z, Jin L: Y chromosome Evidence for a northward migration of modern humans
in East Asia during the last Ice Age. Am J Hum Genet 1999;65:1718-1724.
Xiong M, Jin L: Combined linkage and linkage disequilibrium mapping for genome
screens. Genet Epidemio 2000;19:211-234.
Qian Y, Qian B, Su B, Chu Z,
Ke Y, Yu J, Shi L, Chu J, Lu D, Jin L: Multiple Origins of Tibetan Y Chromosomes.
Hum Genet 2000;106:453-454.
Jin L, Baskett ML, Cavalli-Sforza LL, Zhivotovsky
LA, Feldman MW, Rosenberg NA: A comparison of two microsatellite data sets from
the same human populations. Ann Hum Genet 2000;64:117-134.
Su B, Jin L, Underhill P, Martinson J, Saha N, McGarvey ST, Shriver MD, Chu J, Oefner P,
Chakraborty R, Deka R: Polynesian origins: new insights from the Y-chromosome.
Proc Natl Acad Sci USA 2000 ; 97:8225-8228.
Su B, Sun G, Xiao J, Hu
F, Lu D, Chakraborty R, Deka R, Jin L : Distribution of three HIV-1 resistant
polymorphisms (SDF1-3’A, CCR2-64I, and CCR5-D32) in global populations. Eur J
Hum Genet 2000;8:975-979.
Zhao Z, Jin L, Fu YX, Ramsay M, Jenkins T,
Leskinen E, Pamilo P, Trexler M, Patthy L, Jorde LB, Ramos-Onsins S, Yu N, Li
WH: Worldwide DNA sequence variation in a 10 kb noncoding region on human chromosome
22. Proc Natl Acad Sci USA 2000;97:11354-11358.
Xiong M, Jin L, Li W,
Boerwinkle E: Computational Methods for Gene Expression-Based Tumor Classification.
Biotechniques 2000;29:1264-1270.
Underhill PA, Shen P, Lin AA, Jin L,
Passarino G, Yang WH, Kauffman E, Dietrich FS, Kidd J, Mehdi SQ, Jenkins T, Wells
RS, Seielstad MT, Ibrahim M, Francalacci P, Bertranpetit J, Davis RW, Cavalli-Sforza
LL, Oefner PJ: Y Chromosome Sequence Variation and the History of Human Populations.
Nature Genet 2000;26:358-361.
Su B, Xiao C, Deka R, Seielstad MT, Kangwanpong
D, Xiao J, Lu D, Underhill P, Cavalli-Sforza LL, Chakraborty R, Jin L: Y chromosome
haplotypes reveal prehistorical migrations to the Himalayas. Hum Genet 2000;107:582-590.
Jin L, Su B: Natives or immigrants : origin and migrations of modern humans
in East Asia. Nature Rev Genet 2000;1:126-133.
Akey J, Jin L, Xiong M:
Haplotypes vs single marker linkage disequilibrium tests: what do we gain? Eur
J Hum Genet 2001;9:291-300.
Ke Y, Su B, Song X, Lu D, Chen L, Li H,
Qi C, Marzuki S, Deka R, Oefner P, Underhill PA, Xiao C, Shriver MS, Lell, J,
Wallace D, Wells RS, Seielstad M, Zhu D, Huang W, Chakraborty R, Chen Z, Jin L:
African origin of modern humans in East Asia: A tale of 12,000 Y chromosomes.
Science 2001;292:1151-1153.
Akey JM, Zhang K, Xiong M, Jin L: The affect
of genotyping errors on the robustness of common linkage disequilibrium measures.
Am J Hum Genet 2001; 68:1147-1456.
Akey JM, Wang H, Xiong M, Wu H, Liu
W, Shriver MD, Jin L: Interaction between the melanocortin-1 receptor and OCA2
contributes to inter-individual variation in skin pigmentation phenotypes in a
Tibetan population. Hum Genet 2001;108:516-520.
Jiang Z, Akey J, Shi
J, Xiong M, Wang Y, Shen Y, Xu X, Chen H, Wu H, Xiao J, Lu D, Huang W, Jin L:
A polymorphism in the promoter region of catalase is associated with blood pressure
levels. Hum Genet 2001;109:95-98.
Xiong M, Li W, Zhao J, Jin L, Boerwinkle
E: Gene Selection in Gene Expression Based Tumor Classification. Mol Metab 2001;
73:239-247.
Jin L, Su B: Response to Y Chromosome Replacement? Science 2001; 293:567A-567B.
Wells RS, Yuldasheva N, Ruzibakiev R, Underhill PA, Evseeva I, Blue-Smith J, Jin L, Su B, Pitchappan R, Shanmugalakshmi S, Balakrishnan K, Read M, Pearson NM, Zerjal T, Webster MT, Zholoshvili I, Jamarjashvili E, Gambarov S, Nikbin B, Dostiev A, Aknazarov O, Zalloua P, Tsoy I, Kitaev M, Mirrakhimov M, Chariev A, Bodmer WF. 2001. The Eurasian Heartland: A continental perspective on Y-chromosome diversity. Proceedings of National Academy of Sciences, USA. 98:10244-10249.
Lell JT, Sukernik RI, Starikovskaya YB, Su B, Jin L, Schurr TG, Underhill PA, Wallace DC. 2002. The Dual Origin and Siberian Affinities of Native American Y Chromosomes. American Journal of Human Genetics 70:192-206.
Betran E, Wang W, Jin L, Long M. 2002. Evolution of the Phosphoglycerate mutase processed gene in human and chimpanzee revealing the origin of a new primate gene. Molecular Biology and Evolution. 19:654-663.
Xiong M, Fan R, Jin L. 2002. Linkage disequilibrium mapping of quantitative trait loci under truncation selection. Human Heredity. 53:158-172.
Akey DT, Akey JM, Zhang K, Jin L. 2002. High-throughput melting curve based approaches to assay DNA methylation. Genomics 80:376-384.
Wang N, Josh AM, Zhang K, Chakraborty R, Jin L. 2002. Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. American Journal of Human Genetics 71:1227-1234.
Akey JM, Zhang G, Zhang K, Jin L, Shriver MD. 2002. Interrogating a high-density SNP map for signatures of natural selection. Genome Research. 12:1805-1814.
Akey JM, Wakeley J, Zhang K, Xiong M, Jin L. 2003. The effect of single nucleotide polymorphism identification strategies on estimates of linkage disequilibrium. Molecular Biology and Evolution 20:232-242.
Zhang K, Akey JM, Wang N, Xiong M, Chakraborty R, Jin L. 2003. Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: an act of genetic drift. Human Genetics 113:51-59.
Zhang K, Jin L. 2003. HaploBlockFinder: An efficient program for haplotype block analyses. Bioinformatics 19:1-3.
Shriver MD, Parra EJ, Dios S, Bonilla C, Norton H, Jovel C, Pfaff C, Jones C, Massac A, Cameron N, Baron A, Jackson T, Argyropoulos G, Jin L, Hoggart CJ, McKeigue PM, Kittles RA. 2003. Skin pigmentation, biogeographical ancestry and admixture mapping. Hum Genet. 112:387-399.
Shi J, Xi H, Wang Y, Zhang C, Jiang Z, Zhang K, Shen Y, Jin L, Zhang K, Yuang W, Wang Y, Lin J, Hua Q, Wang F, Xu S, Ren S, Xu S, Zhao G, Chen Z, Jin L, Huang Wei. 2003. Divergence of the genes on human chromosome 21 between human and other hominoids and variation of substitution rates among transcription units. Proceeding of National Academy of Sciences, USA (In press).
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